NXF7 DEFICIENCY IMPAIRS SOCIAL EXPLORATION AND SPATIO-COGNITIVE ABILITIES AS WELL AS HIPPOCAMPAL SYNAPTIC PLASTICITY IN MICE

Nxf7 deficiency impairs social exploration and spatio-cognitive abilities as well as hippocampal synaptic plasticity in mice

Nuclear RNA export factors (NXF) are conserved in all metazoans and are deemed essential for shuttling RNA across the nuclear envelope and other post-transcriptional processes (such as mRNA metabolism, storage Batteries and stability).Disruption of human NXF5 has been implicated in intellectual and psychosocial disabilities.In the present report, w

read more




The outpatient management of hypertension at two Sierra Leonean health centres: A mixed-method investigation of follow-up compliance and patient-reported barriers to care

Background: Sub-Saharan Africa faces an increasing burden of non-communicable diseases.In particular, hypertension and its therapeutic control present a challenge and opportunity for health practitioners and health systems within the region.Aim: This study sought to assess an initiative conducted by two health clinics to begin treatment of hyperten

read more